28/10/2020
DGPPN congress • November 26-28, 2020, online

GCBS Symposium: S-003 Von der Neurophysiologie zur Therapie: neue Ergebnisse zu Hirnstimulationsverfahren aus dem German Center for Brain Stimulation BMBF-Verbundprojekt
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15/10/2020
Action Days Mental Health Research Network • 26 - 28 October 2020

The action days are in German language. On Monday 26.10.2020 there will be a lecture of our working group on the topic "Neuromodulation and multimodal NeuroImaging".
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16/10/2020
DGKN conference 2020 • November 10–14, 2020

- 64. Jahrestagung der deutschen Gesellschaft für Klinische Neurophysiologie und Funktionelle Bildgebung - 7th International Conference on Non-Invasive Brain Stimulation - 4th European Conference of Brain Stimulation in Psychiatry
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27/05/2020
OHBM Annual Meeting 2020 • June 23 - July 3, 2020

This year's meeting of the Organization for Human Brain Mapping (OHBM) is also taking place as an online conference. OHBM is the most well-known multimodal neuroimaging conference with thousands of participants.
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17/05/2020
BrainSTIM conference 2020 • May 19–20, 2020

The Brain Stimulation and Imaging (BrainSTIM) Conference 2020 was originally planned to be held in Finland and was moved to online format due to Covid-19 situation. In previous years the conference was held as a pre-conference of the Human Brain Mapping (OHBM) meeting and was planned as a separate international conference in 2020.
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Publications

lab publications (2007-2021)

 

Prepublications

Brouwer RM, Klein M, ..., Karali T, Keeser D, ..., Thompson PM, Pol HEH. Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan. bioRxiv 2020.04.24.031138; doi: https://doi.org/10.1101/2020.04.24.031138. 

Ekthiari H, ..., Keeser D, ..., Bikson M. A Checklist for Assessing the Methodological Quality of Concurrent tES-fMRI Studies (ContES Checklist): A Consensus Study and Statement. medRxiv 2020.12.23.20248579; doi: https://doi.org/10.1101/2020.12.23.20248579.

 

2022

Uenishi S, Tamaki A, Yamada S, Yasuda K, Ikeda N, Mizutani-Tiebel Y, Keeser D, Padberg F, Tsuji T, Kimoto S, Takahashi S. Computational modeling of electric fields for prefrontal tDCS across patients with schizophrenia and mood disorders. Psychiatry Res Neuroimaging. 2022 Oct;326.111547.

Roell L, Maurus I, Keeser D, Karali T, Papazov B, Hasan A, Schmitt A, Papazova I, Lembeck M, Hirjak D, Sykorova E, Thieme CE, Muenz S, Seitz V, Greska D, Campana M, Wagner E, Loehrs L, Stoecklein S, Ertl-Wagner B, Poemsl J, Roeh A, Malchow B, Keller-Varady K, Meyer-Lindenberg A, Falkai P. Association between aerobic fitness and the functional connectome in patients with schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2022 Oct;272(7).1253-1272.

Maurus I, Roell L, Keeser D, Papazov B, Papazova I, Lembeck M, Roeh A, Wagner E, Hirjak D, Malchow B, Ertl-Wagner B, Stoecklein S, Hasan A, Schmitt A, Meyer- Lindenberg A, Falkai P. Fitness is positively associated with hippocampal formation subfield volumes in schizophrenia. a multiparametric magnetic resonance imaging study. Transl Psychiatry. 2022 Sep 16;12(1).388.

Mizutani-Tiebel Y, Takahashi S, Karali T, Mezger E, Bulubas L, Papazova I, Dechantsreiter E, Stoecklein S, Papazov B, Thielscher A, Padberg F, Keeser D. Differences in electric field strength between clinical and non-clinical populations induced by prefrontal tDCS: A cross-diagnostic, individual MRI-based modeling study. Neuroimage Clin. 2022;34:103011.

Yamada S, Takahashi S, Malchow B, Papazova I, Stöcklein S, Ertl-Wagner B, Papazov B, Kumpf U, Wobrock T, Keller-Varady K, Hasan A, Falkai P, Wagner E, Raabe FJ*, Keeser D*. Cognitive and functional deficits are associated with white matter abnormalities in two independent cohorts of patients with schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2022 Sep;272(6):957-969.

Pross B, Strube W, Papazova I, Güler D, Häckert J, Keeser D, Padberg F, Siamouli M, Falkai P, Hasan A. Anodal transcranial direct current stimulation sustainably increases EEG alpha activity in patients with schizophrenia. Neuropsychopharmacol Rep. 2022 Sep;42(3).323-332.

Maurus I, Röll L, Keeser D, Karali T, Papazov B, Hasan A, Schmitt A, Papazova I, Lembeck M, Hirjak D, Thieme CE, Sykorova E, Münz S, Seitz V, Greska D, Campana M, Wagner E, Löhrs L, Pömsl J, Roeh A, Malchow B, Keller-Varady K, Ertl- Wagner B, Stöcklein S, Meyer-Lindenberg A, Falkai P. Associations between aerobic fitness, negative symptoms, cognitive deficits and brain structure in schizophrenia-a cross-sectional study. Schizophrenia (Heidelb). 2022 Aug 2;8(1).63.

Boudriot E, Schworm B, Slapakova L, Hanken K, Jäger I, Stephan M, Gabriel V, Ioannou G, Melcher J, Hasanaj G, Campana M, Moussiopoulou J, Löhrs L, Hasan A, Falkai P, Pogarell O, Priglinger S, Keeser D, Kern C, Wagner E, Raabe FJ. Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders. Eur Arch Psychiatry Clin Neurosci. 2022 Aug 5.

Rauchmann BS, Brendel M, Franzmeier N, Trappmann L, Zaganjori M, Ersoezlue E, Morenas-Rodriguez E, Guersel S, Burow L, Kurz C, Haeckert J, Tatò M, Utecht J, Papazov B, Pogarell O, Janowitz D, Buerger K, Ewers M, Palleis C, Weidinger E, Biechele G, Schuster S, Finze A, Eckenweber F, Rupprecht R, Rominger A, Goldhardt O, Grimmer T, Keeser D, Stoecklein S, Dietrich O, Bartenstein P, Levin J, Höglinger G, Perneczky R. MicrogliaActivation and Connectivity in Alzheimer Disease and Aging. Ann Neurol. 2022 Aug 1. Epub ahead of print.

Kalman JL, Burkhardt G, Adorjan K, Barton BB, De Jonge S, Eser-Valeri D, Falter-Wagner CM, Heilbronner U, Jobst A, Keeser D, Koenig C, Koller G, Koutsouleris N, Kurz C, Landgraf D, Merz K, Musil R, Nelson AM, Padberg F, Papiol S, Pogarell O, Perneczky R, Raabe F, Reinhard MA, Richter A, Rüther T, Simon MS, Schmitt A, Slapakova L, Scheel N, Schüle C, Wagner E, Wichert SP, Zill P, Falkai P, Schulze TG, Schulte EC. Biobanking in everyday clinical practice in psychiatry-The Munich Mental Health Biobank. Front Psychiatry. 2022 Jul 22;13.934640.

Karch S*, Krause D*, Lehnert K, Konrad J, Haller D, Rauchmann BS, Maywald M, Engelbregt H, Adorjan K, Koller G, Reidler P, Karali T, Tschentscher N, Ertl-Wagner B, Pogarell O, Paolini M*, Keeser D*. Functional and clinical outcomes of FMRI-based neurofeedback training in patients with alcohol dependence: a pilot study. Eur Arch Psychiatry Clin Neurosci. 2022 Jun;272(4):557-569.

Krause D, Chrobok A, Karch S, Keeser D, Manz KM, Koch W, Brendel M, Rominger A, Koller G, Behle N, Pogarell O. Binding potential changes of SERT in patients with depression are associated with remission. A prospective [¹²³I]β-CIT-SPECT study. Exp Clin Psychopharmacol. 2022 May 23.

Brouwer RM, Klein M, Grasby KL, Schnack HG, Jahanshad N, Teeuw J, Thomopoulos SI, Sprooten E, Franz CE, Gogtay N, Kremen WS, Panizzon MS, Olde Loohuis LM, Whelan CD, Aghajani M, Alloza C, Alnæs D, Artiges E, Ayesa-Arriola R, Barker GJ, Bastin ME, Blok E, Bøen E, Breukelaar IA, Bright JK, Buimer EEL, Bülow R, Cannon DM, Ciufolini S, Crossley NA, Damatac CG, Dazzan P, de Mol CL, de Zwarte SMC, Desrivières S, Díaz-Caneja CM, Doan NT, Dohm K, Fröhner JH, Goltermann J, Grigis A, Grotegerd D, Han LKM, Harris MA, Hartman CA, Heany SJ, Heindel W, Heslenfeld DJ, Hohmann S, Ittermann B, Jansen PR, Janssen J, Jia T, Jiang J, Jockwitz C, Karali T, Keeser D, Koevoets MGJC, Lenroot RK, Malchow B, Mandl RCW, Medel V, Meinert S, Morgan CA, Mühleisen TW, Nabulsi L, Opel N, de la Foz VO, Overs BJ, Paillère Martinot ML, Redlich R, Marques TR, Repple J, Roberts G, Roshchupkin GV, Setiaman N, Shumskaya E, Stein F, Sudre G, Takahashi S, Thalamuthu A, Tordesillas-Gutiérrez D, van der Lugt A, van Haren NEM, Wardlaw JM, Wen W, Westeneng HJ, Wittfeld K, Zhu AH, Zugman A, Armstrong NJ, Bonfiglio G, Bralten J, Dalvie S, Davies G, Di Forti M, Ding L, Donohoe G, Forstner AJ, Gonzalez-Peñas J, Guimaraes JPOFT, Homuth G, Hottenga JJ, Knol MJ, Kwok JBJ, Le Hellard S, Mather KA, Milaneschi Y, Morris DW, Nöthen MM, Papiol S, Rietschel M, Santoro ML, Steen VM, Stein JL, Streit F, Tankard RM, Teumer A, van 't Ent D, van der Meer D, van Eijk KR, Vassos E, Vázquez-Bourgon J, Witt SH; IMAGEN Consortium, Adams HHH, Agartz I, Ames D, Amunts K, Andreassen OA, Arango C, Banaschewski T, Baune BT, Belangero SI, Bokde ALW, Boomsma DI, Bressan RA, Brodaty H, Buitelaar JK, Cahn W, Caspers S, Cichon S, Crespo-Facorro B, Cox SR, Dannlowski U, Elvsåshagen T, Espeseth T, Falkai PG, Fisher SE, Flor H, Fullerton JM, Garavan H, Gowland PA, Grabe HJ, Hahn T, Heinz A, Hillegers M, Hoare J, Hoekstra PJ, Ikram MA, Jackowski AP, Jansen A, Jönsson EG, Kahn RS, Kircher T, Korgaonkar MS, Krug A, Lemaitre H, Malt UF, Martinot JL, McDonald C, Mitchell PB, Muetzel RL, Murray RM, Nees F, Nenadić I, Oosterlaan J, Ophoff RA, Pan PM, Penninx BWJH, Poustka L, Sachdev PS, Salum GA, Schofield PR, Schumann G, Shaw P, Sim K, Smolka MN, Stein DJ, Trollor JN, van den Berg LH, Veldink JH, Walter H, Westlye LT, Whelan R, White T, Wright MJ, Medland SE, Franke B, Thompson PM, Hulshoff Pol HE. Genetic variants associated with longitudinal changes in brain structure across the lifespan. Nat Neurosci. 2022 Apr;25(4).421-432.

Mizutani-Tiebel Y, Tik M, Chang KY, Padberg F, Soldini A, Wilkinson Z, Voon CC, Bulubas L, Windischberger C, Keeser D. Concurrent TMS-fMRI: Technical Challenges, Developments, and Overview of Previous Studies. Front Psychiatry. 2022 Apr 21;13:825205.

Ekhtiari H, Ghobadi-Azbari P, Thielscher A, Antal A, Li LM, Shereen AD, Cabral-Calderin Y, Keeser D, Bergmann TO, Jamil A, Violante IR, Almeida J, Meinzer M, Siebner HR, Woods AJ, Stagg CJ, Abend R, Antonenko D, Auer T, Bächinger M, Baeken C, Barron HC, Chase HW, Crinion J, Datta A, Davis MH, Ebrahimi M, Esmaeilpour Z, Falcone B, Fiori V, Ghodratitoostani I, Gilam G, Grabner RH, Greenspan JD, Groen G, Hartwigsen G, Hauser TU, Herrmann CS, Juan CH, Krekelberg B, Lefebvre S, Liew SL, Madsen KH, Mahdavifar-Khayati R, Malmir N, Marangolo P, Martin AK, Meeker TJ, Ardabili HM, Moisa M, Momi D, Mulyana B, Opitz A, Orlov N, Ragert P, Ruff CC, Ruffini G, Ruttorf M, Sangchooli A, Schellhorn K, Schlaug G, Sehm B, Soleimani G, Tavakoli H, Thompson B, Timmann D, Tsuchiyagaito A, Ulrich M, Vosskuhl J, Weinrich CA, Zare-Bidoky M, Zhang X, Zoefel B, Nitsche MA, Bikson M. A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist). a consensus study and statement. Nat Protoc. 2022 Mar;17(3).596-617.

2021

Paolini M, Keeser D, Rauchmann BS, Gschwendtner S, Jeanty H,
Reckenfelderbäumer A, Yaseen O, Reidler P, Rabenstein A, Engelbregt HJ, Maywald M, Blautzik J, Ertl-Wagner B, Pogarell O, Rüther T, Karch S. Correlations Between the DMN and the Smoking Cessation Outcome of a Real-Time fMRI Neurofeedback Supported Exploratory Therapy Approach: Descriptive Statistics on Tobacco-Dependent Patients. Clin EEG Neurosci. 2021 Dec 8. Epub ahead of print.

Jahn P, Deak B, Mayr A, Stankewitz A, Keeser D, Griffanti L, Witkovsky V,
Irving S, Schulz E. Intrinsic network activity reflects the ongoing experience
of chronic pain. Sci Rep. 2021 Nov 8;11(1):21870.

Rek SV, Bühner M, Reinhard MA, Freeman D, Keeser D, Adorjan K, Falkai P,
Padberg F. The COVID-19 Pandemic Mental Health Questionnaire (CoPaQ):
psychometric evaluation and compliance with countermeasures in psychiatric
inpatients and non-clinical individuals. BMC Psychiatry. 2021 Aug 31;21(1):426.

Kumpf U, Stadler M, Plewnia C, Bajbouj M, Langguth B, Zwanzger P, Normann C, Keeser D, Schellhorn K, Egert-Schwender S, Berkes S, Palm U, Hasan A, Padberg F. Transcranial Direct Current Stimulation (tDCS) for major depression - Interim analysis of cloud supervised technical data from the DepressionDC trial. Brain Stimul. 2021 Sep-Oct;14(5):1234-1237.

Engelbregt H, Barmentlo M, Keeser D, Pogarell O, Deijen JB. Effects of
binaural and monaural beat stimulation on attention and EEG. Exp Brain Res. 2021 Sep;239(9):2781-2791. doi: 10.1007/s00221-021-06155-z.

Mortazavi M*, Hizarci Ö*, Gerdes LA, Havla J, Kümpfel T, Hohlfeld R, Stöcklein S, Keeser D*, Ertl-Wagner B*. Multiple sclerosis and subclinical neuropathology in healthy individuals with familial risk: A scoping review of MRI studies. Neuroimage Clin. 2021;31:102734. 

Falkai P, Maurus I, Schmitt A, Malchow B, Schneider-Axmann T, Röll L, Papiol
S, Wobrock T, Hasan A, Keeser D. Improvement in daily functioning after aerobic exercise training in schizophrenia is sustained after exercise cessation. Eur Arch Psychiatry Clin Neurosci. 2021 Oct;271(7):1201-1203. 

Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wagner M, Wiltfang J, Yakupov R, Duezel E, Jessen F, Perneczky R; DELCODE study group and the Alzheimer's Disease Neuroimaging Initiative (ADNI). Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cereb Cortex. 2021 Oct 1;31(11):4901-4915.

Beller E, Lorbeer R, Keeser D, Galiè F, Meinel FG, Grosu S, Bamberg F, Storz
C, Schlett CL, Peters A, Schneider A, Linseisen J, Meisinger C, Rathmann W,
Ertl-Wagner B, Stoecklein S. Significant Impact of Coffee Consumption on MR-
Based Measures of Cardiac Function in a Population-Based Cohort Study without Manifest Cardiovascular Disease. Nutrients. 2021 Apr 13;13(4):1275.

Padberg F, Bulubas L, Mizutani-Tiebel Y, Burkhardt G, Kranz GS, Koutsouleris N, Kambeitz J, Hasan A, Takahashi S, Keeser D, Goerigk S, Brunoni AR. The intervention, the patient and the illness - Personalizing non-invasive brain stimulation in psychiatry. Exp Neurol. 2021 Mar 30:113713.

Bulubas L*, Padberg F*, Mezger E, Suen P, Bueno PV, Duran F, Busatto G, Amaro E Jr, Benseñor IM, Lotufo PA, Goerigk S, Gattaz W, Keeser D*, Brunoni AR*. Prefrontal resting-state connectivity and antidepressant response: no associations in the ELECT-TDCS trial. Eur Arch Psychiatry Clin Neurosci. 2021 Feb;271(1):123-134.

*equal contribution

Maurus I, Hasan A, Schmitt A, Roeh A, Keeser D, Malchow B, Schneider-Axmann T, Hellmich M, Schmied S, Lembeck M, Keller-Varady K, Papazova I, Hirjak D, Topor CE, Walter H, Mohnke S, Vogel BO, Wölwer W,  Schneider F, Henkel K, Meyer- Lindenberg A, Falkai P. Aerobic endurance training to improve cognition and enhance recovery in schizophrenia: design and methodology of a multicenter randomized controlled trial. Eur Arch Psychiatry Clin Neurosci. 2021 Mar;271(2):315-324.

Mezger E, Rauchmann BS, Brunoni AR, Bulubas L, Thielscher A, Werle J, Mortazavi M, Karali T, Stöcklein S, Ertl-Wagner B, Goerigk S, Padberg F, Keeser D. Effects of bifrontal transcranial direct current stimulation on brain glutamate levels and resting state connectivity: multimodal MRI data for the cathodal stimulation site. Eur Arch Psychiatry Clin Neurosci. 2021 Feb;271(1):111-122.

Maurus I, Hasan A, Schmitt A, Roeh A, Keeser D, Malchow B, Schneider-Axmann T, Hellmich M, Schmied S, Lembeck M, Keller-Varady K, Papazova I, Hirjak D, Topor CE, Walter H, Mohnke S, Vogel BO, Wölwer W, Schneider F, Henkel K, Meyer-Lindenberg A, Falkai P. Aerobic endurance training to improve cognition and enhance recovery in schizophrenia: design and methodology of a multicenter randomized controlled trial. Eur Arch Psychiatry Clin Neurosci. 2020 Aug 3. doi: 10.1007/s00406-020-01175-2. Epub ahead of print. 

Hansbauer M, Wagner E, Strube W, Röh A, Padberg F, Keeser D, Falkai P, Hasan A. rTMS and tDCS for the treatment of catatonia: A systematic review. Schizophr Res. 2020 Jun 26:S0920-9964(20)30280-2. doi: 10.1016/j.schres.2020.05.028. Epub ahead of print. 

Mezger E, Brunoni AR, Hasan A, Häckert J, Strube W, Keeser D, Padberg F, Palm U. tDCS for auditory verbal hallucinations in a case of schizophrenia and left frontal lesion: efield simulation and clinical results. Neurocase. 2020 Aug;26(4):241-247. doi: 10.1080/13554794.2020.1776334. Epub 2020 Jun 12. 

Galiè F, Rospleszcz S, Keeser D, Beller E, Illigens B, Lorbeer R, Grosu S, Selder S, Auweter S, Schlett CL, Rathmann W, Schwettmann L, Ladwig KH, Linseisen J, Peters A, Bamberg F, Ertl-Wagner B, Stoecklein S. Machine-learning based exploration of determinants of gray matter volume in the KORA-MRI study. Sci Rep. 2020 May 20;10(1):8363. doi: 10.1038/s41598-020-65040-x. 

Takahashi S*, Keeser D*, Rauchmann BS, Schneider-Axmann T, Keller-Varady K, Maurus I, Dechent P, Wobrock T, Hasan A, Schmitt A, Ertl-Wagner B, Malchow B, Falkai P. Effect of aerobic exercise on cortical thickness in patients with schizophrenia-A dataset. Data Brief. 2020 Apr 17;30:105517. doi: 10.1016/j.dib.2020.105517. 

Suen PJC, Doll S, Batistuzzo MC, Busatto G, Razza LB, Padberg F, Mezger E, Bulubas L, Keeser D, Deng ZD, Brunoni AR. Association between tDCS computational modeling and clinical outcomes in depression: data from the ELECT-TDCS trial. Eur Arch Psychiatry Clin Neurosci. 2020 Apr 11. doi: 10.1007/s00406-020-01127-w.


Takahashi S,* Keeser D,* Rauchmann BS, Schneider-Axmann T, Keller-Varady K, Maurus I, Dechent P, Wobrock T, Hasan A, Schmitt A, Ertl-Wagner B, Malchow B, Falkai P. Effect of aerobic exercise combined with cognitive remediation on cortical thickness and prediction of social adaptation in patients with schizophrenia. Schizophr Res. 2020 Feb;216:397-407. doi: 10.1016/j.schres.2019.11.004. 

*equal contribution.

Brunoni AR, Arns M, Baeken C, Blumberger D, Brunelin J, Carpenter LL, Downar J, Keeser D, Langguth B, Rachid F, Sack AT, Vila-Rodriguez F, Padberg F. Mixing Apples and Oranges in Assessing Outcomes of Repetitive Transcranial Stimulation Meta-Analyses. Psychother Psychosom. 2020;89(2):106-107. doi: 10.1159/000504653.


Papiol S, Keeser D, Hasan A, Schneider-Axmann T, Raabe F, Degenhardt F, Rossner MJ, Bickeböller H, Cantuti-Castelvetri L, Simons M, Wobrock T, Schmitt A, Malchow B, Falkai P. Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients. Transl Psychiatry. 2019 Nov 11;9(1):284. doi: 10.1038/s41398-019-0618-z. 

Rauchmann BS, Ghaseminejad F, Keeser D, Keller-Varady K, Schneider-Axmann T, Takahashi S, Karali T, Helms G, Dechent P, Maurus I, Hasan A, Wobrock T, Ertl-Wagner B, Schmitt A, Malchow B, Falkai P. The impact of endurance training and table soccer on brain metabolites in schizophrenia. Brain Imaging Behav. 2020 Apr;14(2):515-526. doi: 10.1007/s11682-019-00198-1. 

Roeh A, Bunse T, Lembeck M, Handrack M, Pross B, Schoenfeld J, Keeser D, Ertl-Wagner B, Pogarell O, Halle M, Falkai P, Hasan A, Scherr J. Running effects on cognition and plasticity (ReCaP): study protocol of a longitudinal examination of multimodal adaptations of marathon running. Res Sports Med. 2020 Apr-Jun;28(2):241-255. doi: 10.1080/15438627.2019.1647205.     

      

2019      

Beller E, Lorbeer R, Keeser D, Schoeppe F, Sellner S, Hetterich H, Bamberg F,  Schlett CL, Peters A, Ertl-Wagner B, Stoecklein S. Hepatic fat is superior to BMI, visceral and pancreatic fat as a potential risk biomarker for neurodegenerative disease. Eur Radiol. 2019 Jun 11. doi: 10.1007/s00330-019-06276-8.        

Maurus I, Hasan A, Röh A, Takahashi S, Rauchmann B, Keeser D, Malchow B, Schmitt A, Falkai P. Neurobiological effects of aerobic exercise, with a focus on patients with schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2019 Aug;269(5):499-515. doi: 10.1007/s00406-019-01025-w.       

Bulubas L*, Padberg F*, Bueno PV, Duran F, Busatto G, Amaro E Jr, Benseñor IM, Lotufo PA, Goerigk S, Gattaz W, Keeser D*, Brunoni AR*. Antidepressant effects of tDCS are associated with prefrontal gray matter volumes at baseline: Evidence from the ELECT-TDCS trial. Brain Stimul. 2019 May 8. pii: S1935-861X(19)30213-X. doi: 10.1016/j.brs.2019.05.006

*equal contribution.     

Karch S*, Paolini M*, Gschwendtner S, Jeanty H, Reckenfelderbäumer A, Yaseen O, Maywald M, Fuchs C, Rauchmann BS, Chrobok A, Rabenstein A, Ertl-Wagner B, Pogarell O, Keeser D*, Rüther T*. Real-Time fMRI Neurofeedback in Patients With Tobacco Use Disorder During Smoking Cessation: Functional Differences and Implications of the First Training Session in Regard to Future Abstinence or Relapse. Front Hum Neurosci. 2019 Mar 4;13:65. doi: 10.3389/fnhum.2019.00065.eCollection 2019. 

*equal contribution.       

Kirsch V, Boegle R, Keeser D, Kierig E, Ertl-Wagner B, Brandt T, Dieterich M. Beyond binary parcellation of the vestibular cortex - A dataset. Data Brief. 2019 Jan 22;23:103666. doi: 10.1016/j.dib.2019.01.014. eCollection 2019 Apr.

2018 

Schmitt A, Maurus I, Rossner MJ, Röh A, Lembeck M, von Wilmsdorff M, Takahashi S, Rauchmann B, Keeser D, Hasan A, Malchow B, Falkai P. Effects of Aerobic Exercise on Metabolic Syndrome, Cardiorespiratory Fitness, and Symptoms in Schizophrenia Include Decreased Mortality. Front Psychiatry. 2018 Dec 21;9:690. doi: 10.3389/fpsyt.2018.00690. eCollection 2018. Review.  

Krause D, Jobst A, Langemak SM, Keeser D, Chrobok AI, Langgartner S, Adorjan K, Gertzen M, Pogarell O, Karch S. Event-Related Potentials Are Associated With Unexpected Gain and Loss: Using a Gambling Paradigm. Clin EEG Neurosci. 2019 May;50(3):154-160. doi: 10.1177/1550059418814987. Epub 2018 Nov 27.

                              
Beller E*, Keeser D*, Wehn A, Malchow B, Karali T, Schmitt A, Papazova I, Papazov B, Schoeppe F, de Figueiredo GN, Ertl-Wagner B, Stoecklein S. T1-MPRAGE and T2-FLAIR segmentation of cortical and subcortical brain regions-an MRI evaluation study. Neuroradiology. 2018 Nov 6. doi: 10.1007/s00234-018-2121-2. [Epub ahead of print]

Rüther T, Schultz Y, Wirth C, Chrobok A, Rabenstein A, Keeser D, Ertl-Wagner B, Pogarell O, Karch S. Effect of smoking status on neuronal responses to graphic cigarette warning labels. PLoS One. 2018 Sep 20;13(9):e0201360. doi: 10.1371/journal.pone.0201360. eCollection 2018.

Kirsch V, Boegle R, Keeser D, Kierig E, Ertl-Wagner B, Brandt T, Dieterich M. Handedness-dependent functional organizational patterns within the bilateral vestibular cortical network revealed by fMRI connectivity based parcellation. Neuroimage. 2018 Sep;178:224-237. doi: 10.1016/j.neuroimage.2018.05.018. Epub 2018 May 19.

Palm U, Kirsch V, Kübler H, Sarubin N, Keeser D, Padberg F, Dieterich M. Transcranial direct current stimulation (tDCS) for treatment of phobic postural vertigo: an open label pilot study. Eur Arch Psychiatry Clin Neurosci. 2018 Apr 6. doi: 10.1007/s00406-018-0894-2. [Epub ahead of print]

Wörsching J, Padberg F, Goerigk S, Heinz I, Bauer C, Plewnia C, Hasan A, Ertl-Wagner B, Keeser D. Testing assumptions on prefrontal transcranial direct current stimulation: Comparison of electrode montages using multimodal fMRI. Brain Stimul. 2018 Sep - Oct;11(5):998-1007. doi: 10.1016/j.brs.2018.05.001. Epub 2018 May 4.
 

2017                                
Brem AK, Lehto SM, Keeser D, Padberg F. There is no magic in speaker policies: creating gender equality at brain stimulation conferences : Editorial II to the supplement from the 2nd European Conference on brain stimulation in psychiatry. Eur Arch Psychiatry Clin Neurosci. 2017 Dec;267(Suppl 2):113-114. doi:10.1007/s00406-017-0854-2.

Padberg F, Brem AK, Palm U, Pogarell O, Hasan A, Brunelin J, Baeken C, Poulet E, Langguth B, Keeser D. Discovering the individual brain: brain stimulation in psychiatry : Editorial I to the supplement from the 2nd European conference on brain stimulation in psychiatry. Eur Arch Psychiatry Clin Neurosci. 2017 Dec;267(Suppl 2):109-112. doi: 10.1007/s00406-017-0853-3.

Palm U, Kumpf U, Behler N, Wulf L, Kirsch B, Wörsching J, Keeser D, Hasan A, Padberg F. Home Use, Remotely Supervised, and Remotely Controlled Transcranial Direct Current Stimulation: A Systematic Review of the Available Evidence. Neuromodulation. 2017 Sep 15. doi: 10.1111/ner.12686.  PDF
                         
Papiol S*, Popovic D*, Keeser D, Hasan A, Schneider-Axmann T, Degenhardt F, Rossner MJ, Bickeböller H, Schmitt A, Falkai P, Malchow B. Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. Transl Psychiatry. 2017 Jun 27;7(6):e1159.  PDF                 
*equal contribution.  

Van Eijk L, Zwijsen SA, Keeser D, Oosterman JM, Pogarell O, Engelbregt H. EEG-neurofeedback training and quality of life of institutionalized elderly women (a pilot study). Adv Gerontol. 2017;30(2):248-254.

Wörsching J, Padberg F, Helbich K, Hasan A, Koch L, Goerigk S, Stoecklein S, Ertl-Wagner B, Keeser D. Test-retest reliability of prefrontal transcranial Direct Current Stimulation (tDCS) effects on functional MRI connectivity in healthy subjects. NeuroImage. Available online 24 April 2017, http://doi.org/10.1016/j.neuroimage.2017.04.052.  PDF             

Kirsch V, Keeser D, Becker-Bense S, Karali T, Ertl-Wagner B, Brandt T, Dieterich M. Vestibular and visual cortex activity during room tilt illusion. J Neurol. 2017 Mar 21. Epub. doi: 10.1007/s00415-017-8457-4.  PDF

Padberg F, Kumpf U, Mansmann U, Palm U, Plewnia C, Langguth B, Zwanzger P, Fallgatter A, Nolden J, Burger M, Keeser D, Rupprecht R, Falkai P, Hasan A, Egert S, Bajbouj M. Prefrontal transcranial direct current stimulation (tDCS) as treatment for major depression: study design and methodology of a multicenter triple blind randomized placebo controlled trial (DepressionDC). Eur Arch Psychiatry Clin Neurosci. 2017 Feb 28. Epub. 
PDF            

2016               
Wörsching J, Padberg F, Ertl-Wagner B, Kumpf U, Kirsch B, Keeser D. Imaging transcranial direct current stimulation (tDCS) of the prefrontal cortex-correlation or causality in stimulation-mediated effects? Neuroscience & Biobehavioral Reviews. 2016;69:333-56.  PDF            

Schmitt A, Rujescu D, Gawlik M, Hasan A, Hashimoto K, Iceta S, Jarema M, Kambeitz J, Kasper S, Keeser D, Kornhuber J, Koutsouleris N, Lanzenberger R, Malchow B, Saoud M, Spies M, Stöber G, Thibaut F, Riederer P, Falkai P; WFSBP Task Force on Biological Markers. Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics. World J Biol Psychiatry. 2016 Sep;17(6):406-28.  PDF
                                      
Palm, U*, Keeser, D*, Hasan, A, Kupka, M, Blautzik, J, Sarubin, N, Kaymakanova, F, Unger, I, Kupka, MJ, Falkai, P, Ertl-Wagner, B,, Padberg, F. Transcranial direct current stimulation (tDCS) changes negative symptoms and resting-state functional MRI connectivity in schizophrenia: A double-blind, sham-controlled, clinical trial. Schizophrenia Bulletin. 2016 Sep;42(5):1253-61.  PDF                                           

Koerte IK, Willems A, Muehlemann M, Moll K, Cornell S, Pixner S, Steffinger D, Keeser D, Heinen F, Kubicki M, Shenton ME, Ertl-Wagner B, Schulte-Körne G. Mathematical Abilities in Dyslexic Children: A Diffusion Tensor Imaging Study. Brain Imaging Behavior. 2016 Sep;10(3):781-91.  PDF           

Malchow B*, Keeser D*, Keller K, Hasan A, Rauchmann BS, Kimura H, Schneider-Axmann T, Dechent P, Gruber O, Ertl-Wagner B, Honer WG, Hillmer-Vogel U, Schmitt A, Wobrock T, Niklas A, Falkai P. Effects of endurance     training on brain structures in chronic schizophrenia patients and healthy controls. Schizophrenia Research. 2016 Jun;173(3):182-91. PDF         *equal contribution

Engelbregt, H, Keeser, D, Suiker, EM, Eichborn, D, Karch, S, Deijen, JB & Pogarell, O. Long-term effects of placebo-controlled prefrontal EEG-neurofeedback training in healthy subjects. Clinical Neurophysiology. 2016 Apr. 127(4):1931-7.  PDF         

Kirsch V, Keeser D, Hergenroeder T, Erat O, Ertl-Wagner B, Brandt T, Dieterich M. Structural and functional connectivity mapping of the vestibular circuitry from human brainstem to cortex. Brain Structure & Function. 2016 Apr. 221(3):1291-308.  PDF   

Karch S, Loy F, Krause D, Schwarz S, Kiesewetter J, Segmiller F, Chrobok AI, Keeser D, Pogarell O. Increased Event-Related Potentials and Alpha-, Beta-, and Gamma-Activity Associated with Intentional Actions. Frontiers in Psychology. 2016 Jan 22;7:7.  PDF                                     

Krause D, Folkerts M, Karch S, Keeser D, Chrobok AI, Zaudig M, Hegerl U, Juckel G, Pogarell O. Prediction of Treatment Outcome in Patients with Obsessive-Compulsive Disorder with Low-Resolution Brain Electromagnetic Tomography: A Prospective EEG Study. Frontiers in Psychology. 2016 Jan 22. 6:1993  PDF   
 
2015                                    
Blautzik, J, Keeser, D, Kirsch, V, Berman, A, Paolini, M, Mueller, S, Coates, U, Reiser, M, Teipel, SJ, Meindl, T. Divergent effects of long-term treatment with Galantamine on the Default-Mode-Network in patients with Alzheimer Disease. European Neuropsychopharmacology. 2015 Dec 10. 26(3):602-13.  PDF

Antal A, Keeser D, Priori A, Padberg F, Nitsche M. Conceptual and Procedural Shortcomings of the Systematic Review "Evidence That Transcranial Direct Current Stimulation (tDCS) Generates Little-to-no Reliable Neurophysiologic Effect Beyond MEP Amplitude Modulation in Healthy Human Subjects: A Systematic Review" by Horvath and Co-workers. Brain Stimulation. 2015 Jul-Aug;8(4):846-9.  PDF

Karch S*, Keeser D*, Hümmer S, Paolini M, Kirsch V, Karali T, Kupka M, Rauchmann BS, Chrobok A, Blautzik J, Koller G, Ertl-Wagner B, Pogarell O. Modulation of Craving Related Brain Responses Using Real-Time fMRI in Patients with Alcohol UseDisorder. PLoS One. 2015 Jul 23;10(7).  PDF         
*equal contribution.          

Groot, E, van Eijk, L, van Spronsrn, M, Maas, Keeser, D, Pogarell, O, Engelbregt, H. Method to predict side effects of cholinesterase inhibitors in patients with cellular degenerative and vascular dementia. Advances in Geriatrics. Volume 2015, Article ID 270657.  PDF

Paolini M, Keeser D, Ingrisch M, Werner N, Kindermann N, Reiser M, Blautzik J. Resting-state networks in healthy adult subjects: a comparison between a 32-element and an 8-element phased array head coil at 3.0 Tesla. Acta Radiology. 2015 May. 56(5):605-13.  PDF                           

Schmitt A, Malchow B, Keeser D, Falkai P, Hasan A. Neurobiology of schizophrenia : New findings from the structure to the molecules. Nervenarzt. 2015 Mar. 86(3):324-6, 328-31.  PDF
                
Gürkov R*, Berman A*, Dietrich O, Flatz W, Jerin C, Krause E, Keeser D*, Ertl-Wagner B*. MR volumetric assessment of endolymphatic hydrops. European Radiology. 2015 Feb;25(2):585-95.  PDF
*equal contribution.                 
                                           
2014
Palm U, Hasan A, Dehning S, Keeser D, Hummel I, Falkai P, Padberg F. Bifrontale transkranielle Gleichstromstimulation zur Behandlung der Schizophrenie - Ein Fallbericht mit Literaturübersicht. Nervenheilkunde (2014) 33: 382-286.  PDF                

Palm U, Feichtner KB, Hasan A, Gauglitz G, Langguth B, Nitsche MA, Keeser D, Padberg F. The role of  contact media at the skin-electrode interface during transcranial Direct Current Stimulation (tDCS). Brain Stimulation. PDF

Mueller S, Costa A, Keeser D, Pogarell O, Berman A, Coates U, Reiser MF, Riedel M, Möller HJ, Ettinger U, Meindl T. The effects of methylphenidate on whole brain intrinsic functional connectivity (2014). Human Brain Mapping; 35(11):5379-5388.  PDF         

Blautzik J, Vetter C, Schneider A, Gutyrchik E, Reinisch V, Keeser D, Paolini M, Pöppel E, Bao Y, Reiser M, Roenneberg T, Meindl T. Dysregulated daily rhythmicity of neuronal resting-state networks in MCI patients. Chronobiology International. 2014 Nov. 31(9):1041-50.  PDF   

2013
Palm U*, Keeser D*, Blautzik J, Pogarell O, Ertl-Wagner B, Kupka MJ, Reiser M, Padberg F. Prefrontal transcranial direct current stimulation (tDCS) changes negative symptoms and functional  connectivity MRI  (fcMRI) in  a  single  case of  treatment- resistant schizophrenia. Schizophrenia Research. Nov; 150(2-3):583-5.(Epub 2013 Sep 21).  PDF            
*equal contribution 

Mueller S*, Keeser D*, Samson AC, Kirsch V, Blautzik J, Grothe M, Erat O, Hegenloh M, Coates U, Reiser MF, Hennig-Fast K, Meindl T. Convergent Findings of Altered Functional and Structural Brain Connectivity in Individuals With High Functioning Autism: A Multimodal MRI Study. PLOS One 2013, Jun 18;8(6):e67329.    PDF
*equal contribution   

Palm, U, Schiller, C, Fintescu, Z, Obermeier, M, Keeser, D, Reisinger, E, Pogarell, O, Nitsche, M.A, Möller, H-J and Padberg F. Transcranial direct current stimulation in therapy-resistant depression: A double-blind,         placebo-controlled study. Brain Stimulation (2013) Brain Stimulation 5(3): 242-251.  PDF                     

Blaschek A*, Keeser D*, Müller S, Koerte IK, Sebastian Schröder A, Müller-Felber W, Heinen F, Ertl-Wagner B. Early White Matter Changes in Childhood Multiple Sclerosis: A Diffusion Tensor Imaging Study. American Journal of Neuroradiology. 34(10):2015-2020. (Epub 2013 May 16).  PDF
*equal contribution.                           

Palm U, Hasan A, Keeser D, Falkai P, Padberg F. Transcranial random noise stimulation for the treatment of negative symptoms in schizophrenia. Schizophrenia Research. 2013 May; 146(1-3):372-3.  PDF

Palm U, Fintescu Z, Obermeier M, Schiller C, Reisinger E, Keeser D, Pogarell O, Bondy B, Zill P, Padberg F. Serum levels of brain-derived neurotrophic factor are unchanged after transcranial direct current  stimulation in treatment-resistant depression. Journal of Affective Disorders (2013 May 7); 150(2):659-663.  PDF
                                        
Palm U, Reisinger E, Keeser D, Kuo MF, Pogarell O, Leicht G, Mulert C, Nitsche MA, Padberg F. Evaluation of sham transcranial direct current stimulation for randomized, placebo-controlled clinical trials. Brain Stimulation (2013 Feb 8.);6(4):690-695.  PDF                  

Blautzik J, Keeser D, Berman A, Paolini M, Kirsch V, Mueller S, Coates U, Reiser M, Teipel SJ, Meindl T. Long-term test-retest reliability of resting-state networks in healthy elderly subjects and with amnestic mild cognitive impairment patients. Journal of Alzheimers Disease. 2013;34(3):741-54.  PDF
                                
Palm U, Hasan A, Keeser D, Bunse T, Padberg F. New brain stimulation methods in psychiatry: transcranial Direct Current Stimulation for the Treatment of Depression. Nervenheilkunde 2013; 32: 866-876.  PDF

Blautzik J, Vetter C, Peres I, Gutyrchik E, Keeser D, Berman A, Kirsch V, Mueller S, Pöppel E, Reiser M, Roenneberg T, Meindl T. Classifying fMRI-derived resting-state connectivity patterns according to their daily rhythmicity. Neuroimage. 71:298-306.  PDF
 
2012                                                                            
Gürkov, R, Flatz, W, Keeser, D, Strupp, M, Ertl-Wagner, B, Krause, E. Effect of standard-dose Betahistine on endolymphatic hydrops: an MRI pilot study. European Archives of Otorhinolaryngol. (2012) 270(4): 1231-1235. 
PDF
                             
Karch, S, Keeser, D, Pogarell, O. Treatment effects in schizophrenia: evidence from neuroimaging. Minerva Psychiatrica 2012 (53): 171-184.  PDF

Engelbregt, HJ, Keeser, D, Promes, VHL, Schouten-Verhagen, S, Deijen, JB (2012). In vivo EEG changes during a panic attack in a patient with specific phobia. Journal of Medical Cases 3 (1): 34-38.  PDF
                                       
2011                     
Mueller, S, Keeser, D, Teipel, S, Meindl, T. Functional and structural magnetic resonance imaging in neuropsychiatric disorders, Part 1: imaging techniques and their application in mild cognitive impairment and Alzheimer's disease. American Journal of Neuroradiology (2012) 33(10):1845-1850.  PDF
               
Mueller, S, Keeser, D, Teipel, S, Meindl, T. Functional and structural magnetic resonance imaging in neuropsychiatric disorders, Part 2: application in schizophrenia and autism. American Journal of Neuroradiology (2011) 33(11):2033-2037.  PDF                


Keeser, D, Meindl, T, Bor, J, Reiser, M, Palm, U, Pogarell, O, Mulert, C, Padberg, F. Prefrontal transcranial Direct Current Stimulation (tDCS) mudulates resting-state functional connectivity in healthy subjects: a functional magnetic resonance imaging (fMRI) study. Journal of Neuroscience. 2011 Oct 26;31(43):15284-93.  PDF
                                       
Keeser D, Padberg F, Reisinger E, Pogarell O, Kirch V, Palm U, Karch S, Möller HJ, Nitsche MA, Mulert C (2011). Prefrontal direct current stimulation modulates resting EEG and  event-related  potentials  in healthy subjects: A standardized low resolution tomography (sLORETA) study. NeuroImage 55(2): 644-657.  PDF
 
2010                                     
Engelbregt, HJ, Kok, G, Vis, R, Keeser, D & Deijen, JB.Instrumentele Conditionering van frontaalkwab activiteit bij gezonde jong-volwassen – Een dubbelblind placebogecontroleerd onderzoek naa EEG-neurofeedback (2010). Dutch Journal of Neuropsychology 5 (1).  PDF

2009
Palm, U, Keeser, D, Schiller, C, Fintescu, Z, Reisinger, E, Baghai, TC, Mulert, C, Padberg, F (2009).Transcranial direct current stimulation in a patient with therapy- resistant major depression. World Journal of Biological Psychiatry 10 (5): 632-635.  PDF               

2008
Palm, U, Keeser, D, Schiller, C, Fintescu, Z, Reisinger, E, Nitsche, M, Padberg, F (2008a). Skin lesions after treatment with transcranial direct current stimulation (tDCS). Brain Stimulation 1, 386-387.  PDF