Human Brain Mapping • Singapore • June 17-21, 2018

2018 OHBM annual meeting
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European Congress of Radiology (ECR) • Symposium, Saturday, March 3, 2018

Psychoradiology: a blend of molecular, functional and structural imaging with a taste of psychology 16:00-17:30, Room E2 Online videos are available, just click on the titles of the talks:
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PING workshop Munich • May 16-17th 2018

Topic: The individual Human Connectome
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Palm U, Kumpf U, Behler N, Wulf L, Kirsch B, Wörsching J, Keeser D, Hasan A, Padberg F. Home Use, Remotely Supervised, and Remotely Controlled Transcranial Direct Current Stimulation: A Systematic Review of the Available Evidence. Neuromodulation. 2017 Sep 15. doi: 10.1111/ner.12686.  PDF
Papiol S*, Popovic D*, Keeser D, Hasan A, Schneider-Axmann T, Degenhardt F, Rossner MJ, Bickeböller H, Schmitt A, Falkai P, Malchow B. Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. Transl Psychiatry. 2017 Jun 27;7(6):e1159.  PDF                 
*equal contribution.  

Van Eijk L, Zwijsen SA, Keeser D, Oosterman JM, Pogarell O, Engelbregt H. EEG-neurofeedback training and quality of life of institutionalized elderly women (a pilot study). Adv Gerontol. 2017;30(2):248-254.

Wörsching J, Padberg F, Helbich K, Hasan A, Koch L, Goerigk S, Stoecklein S, Ertl-Wagner B, Keeser D. Test-retest reliability of prefrontal transcranial Direct Current Stimulation (tDCS) effects on functional MRI connectivity in healthy subjects. NeuroImage. Available online 24 April 2017, http://doi.org/10.1016/j.neuroimage.2017.04.052.  PDF             

Kirsch V, Keeser D, Becker-Bense S, Karali T, Ertl-Wagner B, Brandt T, Dieterich M. Vestibular and visual cortex activity during room tilt illusion. J Neurol. 2017 Mar 21. Epub. doi: 10.1007/s00415-017-8457-4.  PDF

Padberg F, Kumpf U, Mansmann U, Palm U, Plewnia C, Langguth B, Zwanzger P, Fallgatter A, Nolden J, Burger M, Keeser D, Rupprecht R, Falkai P, Hasan A, Egert S, Bajbouj M. Prefrontal transcranial direct current stimulation (tDCS) as treatment for major depression: study design and methodology of a multicenter triple blind randomized placebo controlled trial (DepressionDC). Eur Arch Psychiatry Clin Neurosci. 2017 Feb 28. Epub. 

Wörsching J, Padberg F, Ertl-Wagner B, Kumpf U, Kirsch B, Keeser D. Imaging transcranial direct current stimulation (tDCS) of the prefrontal cortex-correlation or causality in stimulation-mediated effects? Neuroscience & Biobehavioral Reviews. 2016;69:333-56.  PDF            

Schmitt A, Rujescu D, Gawlik M, Hasan A, Hashimoto K, Iceta S, Jarema M, Kambeitz J, Kasper S, Keeser D, Kornhuber J, Koutsouleris N, Lanzenberger R, Malchow B, Saoud M, Spies M, Stöber G, Thibaut F, Riederer P, Falkai P; WFSBP Task Force on Biological Markers. Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics. World J Biol Psychiatry. 2016 Sep;17(6):406-28.  PDF
Palm, U*, Keeser, D*, Hasan, A, Kupka, M, Blautzik, J, Sarubin, N, Kaymakanova, F, Unger, I, Kupka, MJ, Falkai, P, Ertl-Wagner, B,, Padberg, F. Transcranial direct current stimulation (tDCS) changes negative symptoms and resting-state functional MRI connectivity in schizophrenia: A double-blind, sham-controlled, clinical trial. Schizophrenia Bulletin. 2016 Sep;42(5):1253-61.  PDF                                           

Koerte IK, Willems A, Muehlemann M, Moll K, Cornell S, Pixner S, Steffinger D, Keeser D, Heinen F, Kubicki M, Shenton ME, Ertl-Wagner B, Schulte-Körne G. Mathematical Abilities in Dyslexic Children: A Diffusion Tensor Imaging Study. Brain Imaging Behavior. 2016 Sep;10(3):781-91.  PDF           

Malchow B*, Keeser D*, Keller K, Hasan A, Rauchmann BS, Kimura H, Schneider-Axmann T, Dechent P, Gruber O, Ertl-Wagner B, Honer WG, Hillmer-Vogel U, Schmitt A, Wobrock T, Niklas A, Falkai P. Effects of endurance     training on brain structures in chronic schizophrenia patients and healthy controls. Schizophrenia Research. 2016 Jun;173(3):182-91. PDF         *equal contribution

Engelbregt, H, Keeser, D, Suiker, EM, Eichborn, D, Karch, S, Deijen, JB & Pogarell, O. Long-term effects of placebo-controlled prefrontal EEG-neurofeedback training in healthy subjects. Clinical Neurophysiology. 2016 Apr. 127(4):1931-7.  PDF         

Kirsch V, Keeser D, Hergenroeder T, Erat O, Ertl-Wagner B, Brandt T, Dieterich M. Structural and functional connectivity mapping of the vestibular circuitry from human brainstem to cortex. Brain Structure & Function. 2016 Apr. 221(3):1291-308.  PDF   

Karch S, Loy F, Krause D, Schwarz S, Kiesewetter J, Segmiller F, Chrobok AI, Keeser D, Pogarell O. Increased Event-Related Potentials and Alpha-, Beta-, and Gamma-Activity Associated with Intentional Actions. Frontiers in Psychology. 2016 Jan 22;7:7.  PDF                                     

Krause D, Folkerts M, Karch S, Keeser D, Chrobok AI, Zaudig M, Hegerl U, Juckel G, Pogarell O. Prediction of Treatment Outcome in Patients with Obsessive-Compulsive Disorder with Low-Resolution Brain Electromagnetic Tomography: A Prospective EEG Study. Frontiers in Psychology. 2016 Jan 22. 6:1993  PDF   
Blautzik, J, Keeser, D, Kirsch, V, Berman, A, Paolini, M, Mueller, S, Coates, U, Reiser, M, Teipel, SJ, Meindl, T. Divergent effects of long-term treatment with Galantamine on the Default-Mode-Network in patients with Alzheimer Disease. European Neuropsychopharmacology. 2015 Dec 10. 26(3):602-13.  PDF

Antal A, Keeser D, Priori A, Padberg F, Nitsche M. Conceptual and Procedural Shortcomings of the Systematic Review "Evidence That Transcranial Direct Current Stimulation (tDCS) Generates Little-to-no Reliable Neurophysiologic Effect Beyond MEP Amplitude Modulation in Healthy Human Subjects: A Systematic Review" by Horvath and Co-workers. Brain Stimulation. 2015 Jul-Aug;8(4):846-9.  PDF

Karch S*, Keeser D*, Hümmer S, Paolini M, Kirsch V, Karali T, Kupka M, Rauchmann BS, Chrobok A, Blautzik J, Koller G, Ertl-Wagner B, Pogarell O. Modulation of Craving Related Brain Responses Using Real-Time fMRI in Patients with Alcohol UseDisorder. PLoS One. 2015 Jul 23;10(7).  PDF         
*equal contribution.          

Groot, E, van Eijk, L, van Spronsrn, M, Maas, Keeser, D, Pogarell, O, Engelbregt, H. Method to predict side effects of cholinesterase inhibitors in patients with cellular degenerative and vascular dementia. Advances in Geriatrics. Volume 2015, Article ID 270657.  PDF

Paolini M, Keeser D, Ingrisch M, Werner N, Kindermann N, Reiser M, Blautzik J. Resting-state networks in healthy adult subjects: a comparison between a 32-element and an 8-element phased array head coil at 3.0 Tesla. Acta Radiology. 2015 May. 56(5):605-13.  PDF                           

Schmitt A, Malchow B, Keeser D, Falkai P, Hasan A. Neurobiology of schizophrenia : New findings from the structure to the molecules. Nervenarzt. 2015 Mar. 86(3):324-6, 328-31.  PDF
Gürkov R*, Berman A*, Dietrich O, Flatz W, Jerin C, Krause E, Keeser D*, Ertl-Wagner B*. MR volumetric assessment of endolymphatic hydrops. European Radiology. 2015 Feb;25(2):585-95.  PDF
*equal contribution.                 
Palm U, Hasan A, Dehning S, Keeser D, Hummel I, Falkai P, Padberg F. Bifrontale transkranielle Gleichstromstimulation zur Behandlung der Schizophrenie - Ein Fallbericht mit Literaturübersicht. Nervenheilkunde (2014) 33: 382-286.  PDF                

Palm U, Feichtner KB, Hasan A, Gauglitz G, Langguth B, Nitsche MA, Keeser D, Padberg F. The role of  contact media at the skin-electrode interface during transcranial Direct Current Stimulation (tDCS). Brain Stimulation. PDF

Mueller S, Costa A, Keeser D, Pogarell O, Berman A, Coates U, Reiser MF, Riedel M, Möller HJ, Ettinger U, Meindl T. The effects of methylphenidate on whole brain intrinsic functional connectivity (2014). Human Brain Mapping; 35(11):5379-5388.  PDF         

Blautzik J, Vetter C, Schneider A, Gutyrchik E, Reinisch V, Keeser D, Paolini M, Pöppel E, Bao Y, Reiser M, Roenneberg T, Meindl T. Dysregulated daily rhythmicity of neuronal resting-state networks in MCI patients. Chronobiology International. 2014 Nov. 31(9):1041-50.  PDF   

Palm U*, Keeser D*, Blautzik J, Pogarell O, Ertl-Wagner B, Kupka MJ, Reiser M, Padberg F. Prefrontal transcranial direct current stimulation (tDCS) changes negative symptoms and functional  connectivity MRI  (fcMRI) in  a  single  case of  treatment- resistant schizophrenia. Schizophrenia Research. Nov; 150(2-3):583-5.(Epub 2013 Sep 21).  PDF            
*equal contribution 

Mueller S*, Keeser D*, Samson AC, Kirsch V, Blautzik J, Grothe M, Erat O, Hegenloh M, Coates U, Reiser MF, Hennig-Fast K, Meindl T. Convergent Findings of Altered Functional and Structural Brain Connectivity in Individuals With High Functioning Autism: A Multimodal MRI Study. PLOS One 2013, Jun 18;8(6):e67329.    PDF
*equal contribution   

Palm, U, Schiller, C, Fintescu, Z, Obermeier, M, Keeser, D, Reisinger, E, Pogarell, O, Nitsche, M.A, Möller, H-J and Padberg F. Transcranial direct current stimulation in therapy-resistant depression: A double-blind,         placebo-controlled study. Brain Stimulation (2013) Brain Stimulation 5(3): 242-251.  PDF                     

Blaschek A*, Keeser D*, Müller S, Koerte IK, Sebastian Schröder A, Müller-Felber W, Heinen F, Ertl-Wagner B. Early White Matter Changes in Childhood Multiple Sclerosis: A Diffusion Tensor Imaging Study. American Journal of Neuroradiology. 34(10):2015-2020. (Epub 2013 May 16).  PDF
*equal contribution.                           

Palm U, Hasan A, Keeser D, Falkai P, Padberg F. Transcranial random noise stimulation for the treatment of negative symptoms in schizophrenia. Schizophrenia Research. 2013 May; 146(1-3):372-3.  PDF

Palm U, Fintescu Z, Obermeier M, Schiller C, Reisinger E, Keeser D, Pogarell O, Bondy B, Zill P, Padberg F. Serum levels of brain-derived neurotrophic factor are unchanged after transcranial direct current  stimulation in treatment-resistant depression. Journal of Affective Disorders (2013 May 7); 150(2):659-663.  PDF
Palm U, Reisinger E, Keeser D, Kuo MF, Pogarell O, Leicht G, Mulert C, Nitsche MA, Padberg F. Evaluation of sham transcranial direct current stimulation for randomized, placebo-controlled clinical trials. Brain Stimulation (2013 Feb 8.);6(4):690-695.  PDF                  

Blautzik J, Keeser D, Berman A, Paolini M, Kirsch V, Mueller S, Coates U, Reiser M, Teipel SJ, Meindl T. Long-term test-retest reliability of resting-state networks in healthy elderly subjects and with amnestic mild cognitive impairment patients. Journal of Alzheimers Disease. 2013;34(3):741-54.  PDF
Palm U, Hasan A, Keeser D, Bunse T, Padberg F. New brain stimulation methods in psychiatry: transcranial Direct Current Stimulation for the Treatment of Depression. Nervenheilkunde 2013; 32: 866-876.  PDF

Blautzik J, Vetter C, Peres I, Gutyrchik E, Keeser D, Berman A, Kirsch V, Mueller S, Pöppel E, Reiser M, Roenneberg T, Meindl T. Classifying fMRI-derived resting-state connectivity patterns according to their daily rhythmicity. Neuroimage. 71:298-306.  PDF
Gürkov, R, Flatz, W, Keeser, D, Strupp, M, Ertl-Wagner, B, Krause, E. Effect of standard-dose Betahistine on endolymphatic hydrops: an MRI pilot study. European Archives of Otorhinolaryngol. (2012) 270(4): 1231-1235. 
Karch, S, Keeser, D, Pogarell, O. Treatment effects in schizophrenia: evidence from neuroimaging. Minerva Psychiatrica 2012 (53): 171-184.  PDF

Engelbregt, HJ, Keeser, D, Promes, VHL, Schouten-Verhagen, S, Deijen, JB (2012). In vivo EEG changes during a panic attack in a patient with specific phobia. Journal of Medical Cases 3 (1): 34-38.  PDF
Mueller, S, Keeser, D, Teipel, S, Meindl, T. Functional and structural magnetic resonance imaging in neuropsychiatric disorders, Part 1: imaging techniques and their application in mild cognitive impairment and Alzheimer's disease. American Journal of Neuroradiology (2012) 33(10):1845-1850.  PDF
Mueller, S, Keeser, D, Teipel, S, Meindl, T. Functional and structural magnetic resonance imaging in neuropsychiatric disorders, Part 2: application in schizophrenia and autism. American Journal of Neuroradiology (2011) 33(11):2033-2037.  PDF                

Keeser, D, Meindl, T, Bor, J, Reiser, M, Palm, U, Pogarell, O, Mulert, C, Padberg, F. Prefrontal transcranial Direct Current Stimulation (tDCS) mudulates resting-state functional connectivity in healthy subjects: a functional magnetic resonance imaging (fMRI) study. Journal of Neuroscience. 2011 Oct 26;31(43):15284-93.  PDF
Keeser D, Padberg F, Reisinger E, Pogarell O, Kirch V, Palm U, Karch S, Möller HJ, Nitsche MA, Mulert C (2011). Prefrontal direct current stimulation modulates resting EEG and  event-related  potentials  in healthy subjects: A standardized low resolution tomography (sLORETA) study. NeuroImage 55(2): 644-657.  PDF
Engelbregt, HJ, Kok, G, Vis, R, Keeser, D & Deijen, JB.Instrumentele Conditionering van frontaalkwab activiteit bij gezonde jong-volwassen – Een dubbelblind placebogecontroleerd onderzoek naa EEG-neurofeedback (2010). Dutch Journal of Neuropsychology 5 (1).  PDF

Palm, U, Keeser, D, Schiller, C, Fintescu, Z, Reisinger, E, Baghai, TC, Mulert, C, Padberg, F (2009).Transcranial direct current stimulation in a patient with therapy- resistant major depression. World Journal of Biological Psychiatry 10 (5): 632-635.  PDF               

Palm, U, Keeser, D, Schiller, C, Fintescu, Z, Reisinger, E, Nitsche, M, Padberg, F (2008a). Skin lesions after treatment with transcranial direct current stimulation (tDCS). Brain Stimulation 1, 386-387.  PDF